R&D&I

Companies: AMSlab, AMSbiopharma, Bflow and the Lugo Campus of the University of Santiago de Compostela.

Project: Rapid and automated detection of SARS-Cov-2 based on PCR, nanotechnology and microfluidics (IN852D 2021/5).

Objective: The general objective of this project is the development of a point-of-care system for the detection of SARS-CoV-2 based on molecular techniques and integrating nanotechnology and microfluidics with automation and potential connectivity for its communication.

The consortium that will carry out this project is formed by 3 Galician SMEs: AMSlab (project leader), AMSbiopharma, BFlow and the Lugo Campus of the University of Santiago de Compostela through the Single Molecule Fluorescence research unit, which will collaborate jointly for its execution.

Thus, NANOFLUIDETEC will make use of the incorporation of Essential Enabling Technologies (EET) in the research and development of new products with high added value that allow exploring new markets based on the integration of science and technology, especially in the areas of genetics, nanotechnology, microelectronics, photonics, biotechnology, advanced manufacturing and processing, and their treatment and operability through information and communication technologies (ICT).

Total budget: 258,751.04 €.

This project is subsidised by the Galician Innovation Agency (GAIN), financed by ERDF funds and has the support of the Xunta de Galicia through the second vice-presidency and the Regional Ministry of Economy, Enterprise and Innovation. The operation is funded through the CONECTA COVID 2021 programme under the REACT-EU axis of the Feder Galicia 2014-2020 operational programme, as part of the European Union’s response to the COVID-19 pandemic.

Companies: UTE AMSlab and Nasasbiotech

The Andalusian Health Service (SAS) of the Ministry of Health and Families of the Andalusian Regional Government awarded these Galician biotechs one of the first Public Procurement of Innovation tender dossiers for the Precision Diagnosis and Treatment in Infectious Diseases and Cancer project, called Liquid Biopsy.

This solution aims to establish appropriate clinical guidelines on liquid biopsy analysis that enable the monitoring of patients, as well as the response to treatment in a personalised way, through 2 strategies:

Lot 1: Obtaining and validation of a new diagnostic kit based on the detection and characterisation of circulating tumour DNA (ctDNA) through the LEVA Platform (LiquidBiopsy EV-ctDNAAnalysis), which integrates the purification of extracellular vesicles (EV), DNA extraction and mutation analysis.

Lot 2: Obtaining and validation of a new diagnostic kit based on the detection and characterisation of circulating tumour cells (CTCs) through the ACTUA Platform (Analysis of Circulating Tumour Cells through an Automatic Unit), which integrates the isolation and characterisation of CTCs, the extraction and purification of their DNA, and the analysis of associated mutations, from peripheral blood samples.

The tendered file, Liquid Biopsy, with an execution period of 20 months, is part of the public procurement of innovation initiative, ‘Diagnosis and precision treatment in infectious diseases and cancer’, 80% co-financed with ERDF funds from the Programmes for the Promotion of Innovation from the Demand in Health (FID-SALUD), which is managed by the central government (Ministry of Science and Innovation) in collaboration with the communities, as well as with funds from the Andalusian Health Service.

Specifically, this project is supported by the Agreement signed on 4 December 2017 between the Ministry of Economy, Industry and Competitiveness (currently the Ministry of Science and Innovation) and the Andalusian Health Service.

Total budget of €6,040,784.00.

ERDF co-financing €4,832,627.20.

Total budget of the awarded project: 674,338.84 €.

The Centre for the Development of Industrial Technology (CDTI) has granted AMSlab and ALFREDO IÑESTA funding for the development of a Research and Development project.

The main objective of the research project BIOENTONOMY: NEW BIOECONOMIC STRATEGIES THROUGH INSECT BIOTECHNOLOGY (IDI-20210222), is the development and formulation of new products for the development of new products for the production of insects:

• The development and formulation of new products for use as agricultural inputs from the valorisation of insects fed with agro-industrial waste.
• The study of the protein and lipid fraction from insect biomass showing interesting biological activity.

The project has been planned for a time frame of 36 months starting in September 2020, being executed by ALFREDO IÑESTA and AMSlab in the province of ALICANTE and Lugo respectively, with the collaboration of the Technological Centre Tecnova (located in Almería), the University of Santiago de Compostela, Xenotechs Laboratorios and AMSbiopharma, all three located in Lugo.

The development of the project will involve the mobilisation of investment of 642,774 euros in the total budget.

This project is framed within the call for R&D Projects, subsidised by the CDTI, supported by the Ministry of Science, Innovation and Universities and co-financed with European Union Structural Funds (ERDF) within the “Smart Growth Operational Programme 2014-2020”

This project has been supported by the Ministry of Science, Innovation and Universities and subsidized by the CDTI – Centro para el Desarrollo Tecnológico Industrial– through its call “Misiones Ciencia e Innovación 2019”, co-financed with the European Regional Development Fund -FEDER – through its Pluriregional Operational Program of Spain 2014-2020.

The general objective of the TACTICS project is to demonstrate the viability and suitability of a new chemical analysis technique based on low-field nuclear magnetic resonance (NMR), to facilitate the incorporation of recycled or valued materials in the value chain of Industry 4.0 circular, simplifying and economizing the processes of control of raw materials and products, and providing guarantees on their composition and quality in all links.
As a result, it is expected to obtain a new analysis technique that could be applied in sectors such as agri-food, cosmetics, textiles or the plastics industry. The consortium that gives life to this project is made up entirely of Galician companies: AMSlab (project leader), Sigillum Knowledge Solutions and Torus Software Solutions (TORUSWARE). In addition, it has the scientific collaboration of the company Mestrelab Research and the University of Santiago de Compostela (USC).

Place of execution: Galicia

Execution period: from 08/01/2020 to 12/31/2022

Project budget: 1,598,342.00 euros

Development of an innovation project directly linked to COVID-19: Project «Rapid and simple in-situ molecular detection of SARS-CoV-2, without instrumentation requirement, by means of LAMP». The main objective of the AMSlab group is to develop a LAMP (loop-mediated isothermal amplification) test for the amplification of SARS-CoV-2 genetic material under isothermal conditions and its subsequent visual detection. Project subsidized by the Galician Innovation Agency (GAIN) and supported by the Ministry of Economy, Employment and Industry.

“QC4SUSTEX: Authentication and security of sustainable textiles and development of equipment for the environmental control in their manufacturing” is a research project developed by a consortium of 5 Galician SMEs: AMSLAB, MESTRELAB, ORGANISTRY, 2XMIL and XENOTECHS, further supported by two research groups at the University of Santiago de Compostela and at Citius (IT Singular research centre).

The project is funded by the Galician Innovation Agency (GAIN), through the Conecta-PEME programme and the European Regional Development Fund within the Thematic Objective I, “Strengthening research, technological development and innovation”, included in the framework of programme FEDER Galicia 2014-2020. It also has the support of the Consellería de Economía, Emprego e Industria [Galician Ministry for the Economy, Employment and Industry]. The total budget of the project amounts to 1.384.032,10 €.

The objective of the project is the development of efficient solutions to be sold globally to meet the specific demands of the sustainable fashion market for quality control. The three main objectives of the project are:

• To develop tools for the authentication in the lab of sustainability claims or certifications of fibres and fabrics used in clothes and footwear.
• To evaluate and improve the safety of materials used in the manufacturing of sustainable fashion.
• To develop an integral turnkey service to control the environmental impact on water of the suppliers to the main textile retailers. This will include equipment for continuous monitorisation, in-situ sampling solutions for inspections and an application for the in-situ determination of chemical substances by colorimetry.

At the end of this project, the following RESULTS have been achieved.

Industrial Research to discover new immunotherapy drugs for the treatment of colon cancer

The main objective of the IO4COLON project is the discovery and preclinical development of new medicinal product candidates for the treatment of colon cancer by activating the immune system (IS), to be used in monotherapy, or in combination with each other or with other therapeutic agents. The project is being led by the companies Oncostellae, GalChimia and AMSLab, with the support of the University of Santiago de Compostela, LEITAT Technological Centre and the companies Palo Biofarma, IDIFARMA and Eurofins.

IO4COLON will study the efficacy of two new medicinal products, an ALK5 inhibitor and a GR antagonist, through various mechanisms, while also studying their synergistic effect in the treatment of colon cancer. IO4COLON also represents a considerable qualitative leap in comparison to previous projects, as the aim is to complete Preclinical Development, Pharmaceutical Development, the production of capsules for clinical trials, the preparation of the regulatory documentation and the potential use of the results by applying for new invention patents.

In the second year of the project, significant progress has been made.

At the end of this project, the following RESULTS have been achieved.

This project was subsidised by the Galician Innovation Agency (GAIN), through the CONECTA-PEME Programme, and the European Regional Development Fund within thematic objective 1, “Strengthening research, technological development and innovation“, included within the framework of the FEDER Galicia 2014-2020 operational programme, and will also be supported by the Consellería de Economía, Emprego e Industria [Galician Ministry for the Economy, Employment and Industry]. Total project budget: 1,095,700.00 euros